Cargando…

E35 ablates acute leukemia stem and progenitor cells in vitro and in vivo

Leukemia stem cells (LSCs) have critical functions in acute leukemia (AL) pathogenesis, participating in its initiation and relapse. Thus, identifying new molecules to eradicate LSCs represents a high priority for AL management. This work identified E35, a novel Emodin derivative, which strongly inh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yingyu, Zheng, Jing, Gan, Donghui, Chen, Yanxin, Zhang, Na, Chen, Yuwen, Lin, Zhenxing, Wang, Wenfeng, Chen, Haijun, Lin, Donghong, Hu, Jianda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540425/ https://www.ncbi.nlm.nih.gov/pubmed/31960417 http://dx.doi.org/10.1002/jcp.29457

Ejemplares similares

Doxorubicin/Nucleophosmin Binding Protein-Conjugated Nanoparticle Enhances Anti-leukemia Activity in Acute Lymphoblastic Leukemia Cells in vitro and in vivo
por: Gan, Donghui, et al.
Publicado: (2021)

In Vitro Investigation of the Cytotoxic Activity of Emodin 35 Derivative on Multiple Myeloma Cell Lines
por: Zheng, Jing, et al.
Publicado: (2021)

Integrated bioinformatics analysis of the crucial candidate genes and pathways associated with glucocorticoid resistance in acute lymphoblastic leukemia
por: Chen, Yanxin, et al.
Publicado: (2020)

Association of Platelet Desialylation and Circulating Follicular Helper T Cells in Patients With Thrombocytopenia
por: Chen, Yuwen, et al.
Publicado: (2022)

Platelet desialylation and TFH cells–the novel pathway of immune thrombocytopenia
por: Chen, Yuwen, et al.
Publicado: (2021)

Effect of nucleolin on adriamycin resistance via the regulation of B‐cell lymphoma 2 expression in Burkitt's lymphoma cells
por: Mei, Xuqiao, et al.
Publicado: (2019)

Nucleophosmin1 (NPM1) abnormality in hematologic malignancies, and therapeutic targeting of mutant NPM1 in acute myeloid leukemia
por: Chen, Yingyu, et al.
Publicado: (2020)

P338: SLC7A11 PROMOTES ARGININE BIOSYNTHESIS IN ACUTE LYMPHOBLASTIC LEUKEMIA WITH IMMUNOTHERAPEUTIC POTENTIAL
por: LI, Jiazheng, et al.
Publicado: (2023)

Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells
por: Ding, Yahui, et al.
Publicado: (2016)

Correction to: Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells
por: Ding, Yahui, et al.
Publicado: (2021)

Identification of Early Recurrence Factors in Childhood and Adolescent B-Cell Acute Lymphoblastic Leukemia Based on Integrated Bioinformatics Analysis
por: Huang, Yan, et al.
Publicado: (2020)

PRL-3 exerts oncogenic functions in myeloid leukemia cells via aberrant dephosphorylation of stathmin and activation of STAT3 signaling
por: Xu, Jianping, et al.
Publicado: (2019)

Comparative Study of Nanosecond Electric Fields In Vitro and In Vivo on Hepatocellular Carcinoma Indicate Macrophage Infiltration Contribute to Tumor Ablation In Vivo
por: Chen, Xinhua, et al.
Publicado: (2014)

Hemophilia a patients with inhibitors: Mechanistic insights and novel therapeutic implications
por: Luo, Liping, et al.
Publicado: (2022)

Tanshinone IIA inhibits angiogenesis in human endothelial progenitor cells in vitro and in vivo
por: Lee, Hsiang-Ping, et al.
Publicado: (2017)

PB2294: DOSE-ADJUSTED EDOCH AS FIRST-LINE THERAPY IMPROVED PROGNOSIS OF ADULT T-CELL LEUKEMIA/LYMPHOMA: A 11-YEAR MULTICENTER RETROSPECTIVE STUDY IN CHINA
por: Luo, Luting, et al.
Publicado: (2023)

Chidamide and apatinib are therapeutically synergistic in acute myeloid leukemia stem and progenitor cells
por: Zhao, Haijun, et al.
Publicado: (2022)

Ablation of caspase-1 protects against TBI-induced pyroptosis in vitro and in vivo
por: Liu, Wei, et al.
Publicado: (2018)

Effects of androgens on endothelial progenitor cells in vitro and in vivo
por: Fadini, Gian Paolo, et al.
Publicado: (2009)

Valproic acid increases CAR T cell cytotoxicity against acute myeloid leukemia
por: Wen, Jingjing, et al.
Publicado: (2023)

The synergic effect of vincristine and vorinostat in leukemia in vitro and in vivo
por: Chao, Min-Wu, et al.
Publicado: (2015)

Adult Cardiac Progenitor Cell Aggregates Exhibit Survival Benefit Both In Vitro and In Vivo
por: Bauer, Michael, et al.
Publicado: (2012)

(−)-Gochnatiolide B, synthesized from dehydrocostuslactone, exhibits potent anti-bladder cancer activity in vitro and in vivo
por: Chen, Yuwen, et al.
Publicado: (2018)

GPKOW is essential for pre-mRNA splicing in vitro and suppresses splicing defect caused by dominant-negative DHX16 mutation in vivo
por: Zang, Shengbing, et al.
Publicado: (2014)

Hydroquinone stimulates granulocyte-macrophage progenitor cells in vitro and in vivo.
por: Henschler, R, et al.
Publicado: (1996)

Anticoccidial activity of natural plants extracts mixture against Eimeria tenella: An in vitro and in vivo study
por: Han, Mingzheng, et al.
Publicado: (2022)

IL-35 subunit EBI3 alleviates bleomycin-induced pulmonary fibrosis via suppressing DNA enrichment of STAT3
por: Chen, Donghong, et al.
Publicado: (2021)

In Vitro and In Vivo Investigation of High-Intensity Focused Ultrasound (HIFU) Hat-Type Ablation Mode
por: Dai, Hongya, et al.
Publicado: (2017)

PDGFRβ(+)/c-kit(+) pulp cells are odontoblastic progenitors capable of producing dentin-like structure in vitro and in vivo
por: Cai, Shiwei, et al.
Publicado: (2016)

ABL Genomic Editing Sufficiently Abolishes Oncogenesis of Human Chronic Myeloid Leukemia Cells In Vitro and In Vivo
por: Chen, Shu-Huey, et al.
Publicado: (2020)

Neuroprotective effects of 3,5-di-o-caffeoylquinic acid in vitro and in vivo
por: Han, Junkyu, et al.
Publicado: (2011)

SATB1 Expression Is Associated with Biologic Behavior in Colorectal Carcinoma In Vitro and In Vivo
por: Zhang, Jie, et al.
Publicado: (2013)

Characterization and analysis of long non-coding rna (lncRNA) in In Vitro- and Ex Vivo-derived cardiac progenitor cells
por: Arnone, Baron, et al.
Publicado: (2017)

CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo
por: Dietrich, Joerg, et al.
Publicado: (2006)

In Vivo and In Vitro Cartilage Differentiation from Embryonic Epicardial Progenitor Cells
por: Palmquist-Gomes, Paul, et al.
Publicado: (2022)

Protocols to generate and isolate mouse myogenic progenitors both in vitro and in vivo
por: Khateb, Mamduh, et al.
Publicado: (2023)

Antimetastatic Potentials of Dioscorea nipponica on Melanoma In Vitro and In Vivo
por: Ho, Mao-Lin, et al.
Publicado: (2011)

Myricetin enhance chemosensitivity of 5-fluorouracil on esophageal carcinoma in vitro and in vivo
por: Wang, Lei, et al.
Publicado: (2014)

Down-regulation of the PI3K/Akt signaling pathway and induction of apoptosis in CA46 Burkitt lymphoma cells by baicalin
por: Huang, Yi, et al.
Publicado: (2012)

Regulatory effects of Zishen Yutai Pill on endometrial epithelial response in vitro in immunology microenvironment
por: Chen, Xiaoli, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_osbhep5niat5srf9221onv70jd