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Crizotinib sensitizes the erlotinib resistant HCC827GR5 cell line by influencing lysosomal function

In non‐small cell lung cancer, sensitizing mutations in epidermal growth factor receptor (EGFR) or cMET amplification serve as good biomarkers for targeted therapies against EGFR or cMET, respectively. Here we aimed to determine how this different genetic background would affect the interaction betw...

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Detalles Bibliográficos
Autores principales: Van Der Steen, Nele, Keller, Kaylee, Dekker, Henk, Porcelli, Letizia, Honeywell, Richard J., Van Meerloo, Johan, Musters, René J. P., Kathmann, Ietje, Frampton, Adam E., Liu, Daniel S. K., Ruijtenbeek, Rob, Rolfo, Christian, Pauwels, Patrick, Giovannetti, Elisa, Peters, Godefridus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540474/
https://www.ncbi.nlm.nih.gov/pubmed/31960422
http://dx.doi.org/10.1002/jcp.29463

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