Identification and characterization of miRNAs during early pregnancy in domestic sheep

MicroRNA resources in sheep are limited compared with those in other domesticated mammalian species. By sequencing small RNAs of sheep corpus luteum and endometrium, we have generated the largest amount of miRNA‐seq data and compiled the most comprehensive list thus far of miRNAs (n = 599) in sheep....

Descripción completa

Detalles Bibliográficos
Autores principales: Pokharel, Kisun, Peippo, Jaana, Li, Meng‐Hua, Kantanen, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540487/
https://www.ncbi.nlm.nih.gov/pubmed/32794198
http://dx.doi.org/10.1111/age.12992
Descripción
Sumario:MicroRNA resources in sheep are limited compared with those in other domesticated mammalian species. By sequencing small RNAs of sheep corpus luteum and endometrium, we have generated the largest amount of miRNA‐seq data and compiled the most comprehensive list thus far of miRNAs (n = 599) in sheep. Additionally, we observed a highly conserved maternally imprinted cluster of miRNAs on chromosome 18 homologous to that found on chromosome 14 in human and several other eutherian mammals.

Ejemplares similares