Identification and characterization of miRNAs during early pregnancy in domestic sheep

MicroRNA resources in sheep are limited compared with those in other domesticated mammalian species. By sequencing small RNAs of sheep corpus luteum and endometrium, we have generated the largest amount of miRNA‐seq data and compiled the most comprehensive list thus far of miRNAs (n = 599) in sheep....

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Autores principales: Pokharel, Kisun, Peippo, Jaana, Li, Meng‐Hua, Kantanen, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540487/
https://www.ncbi.nlm.nih.gov/pubmed/32794198
http://dx.doi.org/10.1111/age.12992
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author Pokharel, Kisun
Peippo, Jaana
Li, Meng‐Hua
Kantanen, Juha
author_facet Pokharel, Kisun
Peippo, Jaana
Li, Meng‐Hua
Kantanen, Juha
author_sort Pokharel, Kisun
collection PubMed
description MicroRNA resources in sheep are limited compared with those in other domesticated mammalian species. By sequencing small RNAs of sheep corpus luteum and endometrium, we have generated the largest amount of miRNA‐seq data and compiled the most comprehensive list thus far of miRNAs (n = 599) in sheep. Additionally, we observed a highly conserved maternally imprinted cluster of miRNAs on chromosome 18 homologous to that found on chromosome 14 in human and several other eutherian mammals.
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spelling pubmed-75404872020-10-09 Identification and characterization of miRNAs during early pregnancy in domestic sheep Pokharel, Kisun Peippo, Jaana Li, Meng‐Hua Kantanen, Juha Anim Genet Short Communications MicroRNA resources in sheep are limited compared with those in other domesticated mammalian species. By sequencing small RNAs of sheep corpus luteum and endometrium, we have generated the largest amount of miRNA‐seq data and compiled the most comprehensive list thus far of miRNAs (n = 599) in sheep. Additionally, we observed a highly conserved maternally imprinted cluster of miRNAs on chromosome 18 homologous to that found on chromosome 14 in human and several other eutherian mammals. John Wiley and Sons Inc. 2020-08-13 2020-10 /pmc/articles/PMC7540487/ /pubmed/32794198 http://dx.doi.org/10.1111/age.12992 Text en © 2020 The Authors. Animal Genetics published by John Wiley & Sons Ltd on behalf of Stichting International Foundation for Animal Genetics This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communications
Pokharel, Kisun
Peippo, Jaana
Li, Meng‐Hua
Kantanen, Juha
Identification and characterization of miRNAs during early pregnancy in domestic sheep
title Identification and characterization of miRNAs during early pregnancy in domestic sheep
title_full Identification and characterization of miRNAs during early pregnancy in domestic sheep
title_fullStr Identification and characterization of miRNAs during early pregnancy in domestic sheep
title_full_unstemmed Identification and characterization of miRNAs during early pregnancy in domestic sheep
title_short Identification and characterization of miRNAs during early pregnancy in domestic sheep
title_sort identification and characterization of mirnas during early pregnancy in domestic sheep
topic Short Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540487/
https://www.ncbi.nlm.nih.gov/pubmed/32794198
http://dx.doi.org/10.1111/age.12992
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AT kantanenjuha identificationandcharacterizationofmirnasduringearlypregnancyindomesticsheep

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