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Agrochemical industry development, trends in R&D and the impact of regulation

Over the last 20 years the share of the crop protection market attributable to the leading markets (North America, EU‐15 and Japan) that are the major focus of new active ingredient research and development (R&D) has declined. Greater growth has been recorded in developing markets, questioning t...

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Detalles Bibliográficos
Autor principal: Phillips, Matthew William Archer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540551/
https://www.ncbi.nlm.nih.gov/pubmed/31858688
http://dx.doi.org/10.1002/ps.5728
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author Phillips, Matthew William Archer
author_facet Phillips, Matthew William Archer
author_sort Phillips, Matthew William Archer
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description Over the last 20 years the share of the crop protection market attributable to the leading markets (North America, EU‐15 and Japan) that are the major focus of new active ingredient research and development (R&D) has declined. Greater growth has been recorded in developing markets, questioning the focus of current R&D strategy. R&D budgets within the major companies have seen a shift toward genetically modified (GM) trait development away from agrochemicals, such that the rate of new active ingredients entering development and subsequently being introduced has declined. As a result, the industry has become more reliant on older, off‐patent chemistry, although the availability of older products has been affected by re‐registration requirements, particularly in the EU. Current criteria often preclude the registration of broad‐spectrum agrochemicals, resulting in many new active ingredients being single site active, which is perceived to increase the potential for resistance development, particularly for herbicides, although this is not always the case. © 2019 The Author. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
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spelling pubmed-75405512020-10-09 Agrochemical industry development, trends in R&D and the impact of regulation Phillips, Matthew William Archer Pest Manag Sci Review Over the last 20 years the share of the crop protection market attributable to the leading markets (North America, EU‐15 and Japan) that are the major focus of new active ingredient research and development (R&D) has declined. Greater growth has been recorded in developing markets, questioning the focus of current R&D strategy. R&D budgets within the major companies have seen a shift toward genetically modified (GM) trait development away from agrochemicals, such that the rate of new active ingredients entering development and subsequently being introduced has declined. As a result, the industry has become more reliant on older, off‐patent chemistry, although the availability of older products has been affected by re‐registration requirements, particularly in the EU. Current criteria often preclude the registration of broad‐spectrum agrochemicals, resulting in many new active ingredients being single site active, which is perceived to increase the potential for resistance development, particularly for herbicides, although this is not always the case. © 2019 The Author. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. John Wiley & Sons, Ltd. 2020-01-29 2020-10 /pmc/articles/PMC7540551/ /pubmed/31858688 http://dx.doi.org/10.1002/ps.5728 Text en © 2019 The Author. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Review
Phillips, Matthew William Archer
Agrochemical industry development, trends in R&D and the impact of regulation
title Agrochemical industry development, trends in R&D and the impact of regulation
title_full Agrochemical industry development, trends in R&D and the impact of regulation
title_fullStr Agrochemical industry development, trends in R&D and the impact of regulation
title_full_unstemmed Agrochemical industry development, trends in R&D and the impact of regulation
title_short Agrochemical industry development, trends in R&D and the impact of regulation
title_sort agrochemical industry development, trends in r&d and the impact of regulation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540551/
https://www.ncbi.nlm.nih.gov/pubmed/31858688
http://dx.doi.org/10.1002/ps.5728
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