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Management of Acute Ischemic Stroke
OBJECTIVES: Concise “synthetic” review of the state of the art of management of acute ischemic stroke. DATA SOURCES: Available literature on PubMed. STUDY SELECTION: We selected landmark studies, recent clinical trials, observational studies, and professional guidelines on the management of stroke i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540624/ https://www.ncbi.nlm.nih.gov/pubmed/32947473 http://dx.doi.org/10.1097/CCM.0000000000004597 |
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author | Herpich, Franziska Rincon, Fred |
author_facet | Herpich, Franziska Rincon, Fred |
author_sort | Herpich, Franziska |
collection | PubMed |
description | OBJECTIVES: Concise “synthetic” review of the state of the art of management of acute ischemic stroke. DATA SOURCES: Available literature on PubMed. STUDY SELECTION: We selected landmark studies, recent clinical trials, observational studies, and professional guidelines on the management of stroke including the last 10 years. DATA EXTRACTION: Eligible studies were identified and results leading to guideline recommendations were summarized. DATA SYNTHESIS: Stroke mortality has been declining over the past 6 decades, and as a result, stroke has fallen from the second to the fifth leading cause of death in the United States. This trend may follow recent advances in the management of stroke, which highlight the importance of early recognition and early revascularization. Recent studies have shown that early recognition, emergency interventional treatment of acute ischemic stroke, and treatment in dedicated stroke centers can significantly reduce stroke-related morbidity and mortality. However, stroke remains the second leading cause of death worldwide and the number one cause for acquired long-term disability, resulting in a global annual economic burden. CONCLUSIONS: Appropriate treatment of ischemic stroke is essential in the reduction of mortality and morbidity. Management of stroke involves a multidisciplinary approach that starts and extends beyond hospital admission. |
format | Online Article Text |
id | pubmed-7540624 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-75406242020-10-14 Management of Acute Ischemic Stroke Herpich, Franziska Rincon, Fred Crit Care Med Concise Definitive Review OBJECTIVES: Concise “synthetic” review of the state of the art of management of acute ischemic stroke. DATA SOURCES: Available literature on PubMed. STUDY SELECTION: We selected landmark studies, recent clinical trials, observational studies, and professional guidelines on the management of stroke including the last 10 years. DATA EXTRACTION: Eligible studies were identified and results leading to guideline recommendations were summarized. DATA SYNTHESIS: Stroke mortality has been declining over the past 6 decades, and as a result, stroke has fallen from the second to the fifth leading cause of death in the United States. This trend may follow recent advances in the management of stroke, which highlight the importance of early recognition and early revascularization. Recent studies have shown that early recognition, emergency interventional treatment of acute ischemic stroke, and treatment in dedicated stroke centers can significantly reduce stroke-related morbidity and mortality. However, stroke remains the second leading cause of death worldwide and the number one cause for acquired long-term disability, resulting in a global annual economic burden. CONCLUSIONS: Appropriate treatment of ischemic stroke is essential in the reduction of mortality and morbidity. Management of stroke involves a multidisciplinary approach that starts and extends beyond hospital admission. Lippincott Williams & Wilkins 2020-11 2020-10-09 /pmc/articles/PMC7540624/ /pubmed/32947473 http://dx.doi.org/10.1097/CCM.0000000000004597 Text en Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Concise Definitive Review Herpich, Franziska Rincon, Fred Management of Acute Ischemic Stroke |
title | Management of Acute Ischemic Stroke |
title_full | Management of Acute Ischemic Stroke |
title_fullStr | Management of Acute Ischemic Stroke |
title_full_unstemmed | Management of Acute Ischemic Stroke |
title_short | Management of Acute Ischemic Stroke |
title_sort | management of acute ischemic stroke |
topic | Concise Definitive Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540624/ https://www.ncbi.nlm.nih.gov/pubmed/32947473 http://dx.doi.org/10.1097/CCM.0000000000004597 |
work_keys_str_mv | AT herpichfranziska managementofacuteischemicstroke AT rinconfred managementofacuteischemicstroke |