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An Amphipathic Alpha‐Helix Guides Maturation of the Ribosomally‐Synthesized Lipolanthines
The recently discovered strongly anti‐Gram‐positive lipolanthines represent a new group of lipidated, ribosomally synthesized and post‐translationally modified peptides (RiPPs). They are bicyclic octapeptides with a central quaternary carbon atom (avionin), which is installed through the cooperative...
Autores principales: | Wiebach, Vincent, Mainz, Andi, Schnegotzki, Romina, Siegert, Mary‐Ann J., Hügelland, Manuela, Pliszka, Nicole, Süssmuth, Roderich D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540663/ https://www.ncbi.nlm.nih.gov/pubmed/32533616 http://dx.doi.org/10.1002/anie.202003804 |
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