Biophysical basis for Kv1.3 regulation of membrane potential changes induced by P2X4‐mediated calcium entry in microglia

Microglia‐mediated inflammation exerts adverse effects in ischemic stroke and in neurodegenerative disorders such as Alzheimer's disease (AD). Expression of the voltage‐gated potassium channel Kv1.3 is required for microglia activation. Both genetic deletion and pharmacological inhibition of Kv...

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Detalles Bibliográficos
Autores principales: Nguyen, Hai M., di Lucente, Jacopo, Chen, Yi‐Je, Cui, Yanjun, Ibrahim, Rania H., Pennington, Michael W., Jin, Lee‐Way, Maezawa, Izumi, Wulff, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540709/
https://www.ncbi.nlm.nih.gov/pubmed/32525239
http://dx.doi.org/10.1002/glia.23847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540709/
https://www.ncbi.nlm.nih.gov/pubmed/32525239
http://dx.doi.org/10.1002/glia.23847

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