Cargando…
Targeting the glycan of receptor binding domain with jacalin as a novel approach to develop a treatment against COVID-19
In silico analysis revealed that a lectin, jacalin from jackfruit seeds, recognizes a glycosylated region of the receptor-binding domain (RBD) of SARS-CoV2. Jacalin binding induces conformational changes in RBD and significantly affects its interaction with human angiotensin-converting enzyme 2. The...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540766/ https://www.ncbi.nlm.nih.gov/pubmed/33047045 http://dx.doi.org/10.1098/rsos.200844 |