Cargando…
CCAR1 and CCAR2 as gene chameleons with antagonistic duality: Preclinical, human translational, and mechanistic basis
Cell Cycle and Apoptosis Regulator 1 (CCAR1) and Cell Cycle and Apoptosis Regulator 2 (CCAR2) have emerged as key players in physiology and pathophysiology, with critical roles in the DNA damage response, nuclear receptor function, and Wnt signaling, among other activities. Contradictory reports exi...
Autores principales: | Johnson, Gavin S., Rajendran, Praveen, Dashwood, Roderick H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540973/ https://www.ncbi.nlm.nih.gov/pubmed/33403784 http://dx.doi.org/10.1111/cas.14579 |
Ejemplares similares
-
Mechanistic insights into the dual role of CCAR2/DBC1 in cancer
por: Kim, Hwa Jin, et al.
Publicado: (2023) -
DBC1/CCAR2 and CCAR1 Are Largely Disordered Proteins that Have Evolved from One Common Ancestor
por: Brunquell, Jessica, et al.
Publicado: (2014) -
Transcriptomic analysis of Streptomyces clavuligerus ΔccaR::tsr: effects of the cephamycin C-clavulanic acid cluster regulator CcaR on global regulation*
por: Álvarez-Álvarez, R, et al.
Publicado: (2014) -
A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection
por: López-Saavedra, Ana, et al.
Publicado: (2016) -
The Overexpression of CCAR1 in Hepatocellular Carcinoma Associates with Poor Prognosis
por: Ha, Sang Yun, et al.
Publicado: (2016)