Effect of murine double‐minute 2 inhibitors in preclinical models of advanced clear cell carcinomas originating from ovaries and kidneys

Advanced clear cell carcinomas originating from both ovaries and kidneys with cancerous peritonitis have poor prognoses. Murine double‐minute 2 (MDM2) is a potential therapeutic target for clear cell ovarian carcinomas with WT TP53. Herein, we characterized the antiangiogenic and antitumor effects o...

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Detalles Bibliográficos
Autores principales: Kawata, Yoshiko, Nagasaka, Kazunori, Oda, Katsutoshi, Makii, Chinami, Takeuchi, Makoto, Oki, Shinya, Honjo, Harunori, Kojima, Machiko, Miyagawa, Yuko, Taguchi, Ayumi, Tanikawa, Michihiro, Sone, Kenbun, Hiraike, Haruko, Matsumoto, Yoko, Wada‐Hiraike, Osamu, Ayabe, Takuya, Osuga, Yutaka, Fujii, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Drug Discovery and Delivery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541011/
https://www.ncbi.nlm.nih.gov/pubmed/32713096
http://dx.doi.org/10.1111/cas.14583

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