Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis

The extracellular matrix (ECM) plays critical roles in tumor progression and metastasis. However, the contribution of ECM proteins to early metastatic onset in the peritoneal cavity remains unexplored. Here, we suggest a new route of metastasis through the interaction of integrin alpha 2 (ITGA2) wit...

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Detalles Bibliográficos
Autores principales: Huang, Yen-Lin, Liang, Ching-Yeu, Ritz, Danilo, Coelho, Ricardo, Septiadi, Dedy, Estermann, Manuela, Cumin, Cécile, Rimmer, Natalie, Schötzau, Andreas, Núñez López, Mónica, Fedier, André, Konantz, Martina, Vlajnic, Tatjana, Calabrese, Diego, Lengerke, Claudia, David, Leonor, Rothen-Rutishauser, Barbara, Jacob, Francis, Heinzelmann-Schwarz, Viola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541088/
https://www.ncbi.nlm.nih.gov/pubmed/33026975
http://dx.doi.org/10.7554/eLife.59442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541088/
https://www.ncbi.nlm.nih.gov/pubmed/33026975
http://dx.doi.org/10.7554/eLife.59442

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