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Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
The extracellular matrix (ECM) plays critical roles in tumor progression and metastasis. However, the contribution of ECM proteins to early metastatic onset in the peritoneal cavity remains unexplored. Here, we suggest a new route of metastasis through the interaction of integrin alpha 2 (ITGA2) wit...
Autores principales: | Huang, Yen-Lin, Liang, Ching-Yeu, Ritz, Danilo, Coelho, Ricardo, Septiadi, Dedy, Estermann, Manuela, Cumin, Cécile, Rimmer, Natalie, Schötzau, Andreas, Núñez López, Mónica, Fedier, André, Konantz, Martina, Vlajnic, Tatjana, Calabrese, Diego, Lengerke, Claudia, David, Leonor, Rothen-Rutishauser, Barbara, Jacob, Francis, Heinzelmann-Schwarz, Viola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541088/ https://www.ncbi.nlm.nih.gov/pubmed/33026975 http://dx.doi.org/10.7554/eLife.59442 |
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