Generation of oligomers of subunit vaccine candidate glycoprotein D of Herpes Simplex Virus-2 expressed in fusion with IgM Fc domain(s) in Escherichia coli: A strategy to enhance the immunogenicity of the antigen

Glycoprotein D (gD) of Herpes Simplex Virus-2 is used as an antigen in various anti-herpes subunit vaccines owing to its involvement in binding the host cell receptors for host infectivity. However, most of these monomeric protein based candidates have shown low immunogenicity in animal models. To e...

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Detalles Bibliográficos
Autores principales: Singh, Vikas Kumar, Kumar, Sandeep, Dhaked, Rajeev Kumar, Ansari, Abdul S., Lohiya, Nirmal K., Tapryal, Suman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541101/
https://www.ncbi.nlm.nih.gov/pubmed/33047090
http://dx.doi.org/10.1007/s13205-020-02452-6

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