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Heterogeneity in VEGF Receptor-2 Mobility and Organization on the Endothelial Cell Surface Leads to Diverse Models of Activation by VEGF

The dynamic nanoscale organization of cell surface receptors plays an important role in signaling. We determine this organization and its relation to activation of VEGF receptor-2 (VEGFR-2), a critical receptor tyrosine kinase in endothelial cells (ECs), by combining single-molecule imaging of endog...

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Detalles Bibliográficos
Autores principales:	da Rocha-Azevedo, Bruno, Lee, Sungsoo, Dasgupta, Aparajita, Vega, Anthony R., de Oliveira, Luciana R., Kim, Tae, Kittisopikul, Mark, Malik, Zachariah A., Jaqaman, Khuloud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541195/ https://www.ncbi.nlm.nih.gov/pubmed/32997988 http://dx.doi.org/10.1016/j.celrep.2020.108187

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