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Prime editing efficiently generates W542L and S621I double mutations in two ALS genes in maize

Prime editing is a novel and universal CRISPR/Cas-derived precision genome-editing technology that has been recently developed. However, low efficiency of prime editing has been shown in transgenic rice lines. We hypothesize that enhancing pegRNA expression could improve prime-editing efficiency. In...

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Detalles Bibliográficos
Autores principales:	Jiang, Yuan-Yuan, Chai, Yi-Ping, Lu, Min-Hui, Han, Xiu-Li, Lin, Qiupeng, Zhang, Yu, Zhang, Qiang, Zhou, Yun, Wang, Xue-Chen, Gao, Caixia, Chen, Qi-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541250/ https://www.ncbi.nlm.nih.gov/pubmed/33023639 http://dx.doi.org/10.1186/s13059-020-02170-5

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