Association between copy-number alteration of +20q, −14q and −18p and cross-sensitivity to tyrosine kinase inhibitors in clear-cell renal cell carcinoma

BACKGROUND: We aim to explore association between copy number alteration (CNA) and sensitivity to common tyrosine kinase inhibitors (TKIs) used in clear-cell renal cell carcinoma (ccRCC) treatment. METHODS: CNA with related sensitivity profiles were extracted from the Genomics of Drug Sensitivity in...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Li, Yuqing, Lyu, Yinfeng, Wen, Hui, Feng, Chenchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541266/
https://www.ncbi.nlm.nih.gov/pubmed/33041663
http://dx.doi.org/10.1186/s12935-020-01585-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541266/
https://www.ncbi.nlm.nih.gov/pubmed/33041663
http://dx.doi.org/10.1186/s12935-020-01585-1

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