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Long noncoding RNA RP11-757G1.5 sponges miR-139-5p and upregulates YAP1 thereby promoting the proliferation and liver, spleen metastasis of colorectal cancer

BACKGROUND: Accumulating evidence indicates that long non-coding RNAs (lncRNAs) acting as crucial regulators in tumorigenesis. However, its biological functions of lncRNAs in colorectal cancer (CRC) have not been systematically clarified. METHODS: An unbiased screening was performed to identify disr...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaojian, Bu, Fanqin, Tan, Ting, Luo, Qilin, Zhu, Jinfeng, Lin, Kang, Huang, Jun, Luo, Chen, Zhu, Zhengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541316/
https://www.ncbi.nlm.nih.gov/pubmed/33023613
http://dx.doi.org/10.1186/s13046-020-01717-5