Disturbed nitric oxide signalling gives rise to congenital bicuspid aortic valve and aortopathy

Patients with a congenital bicuspid aortic valve (BAV), a valve with two instead of three aortic leaflets, have an increased risk of developing thoracic aneurysms and aortic dissection. The mechanisms underlying BAV-associated aortopathy are poorly understood. This study examined BAV-associated aort...

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Detalles Bibliográficos
Autores principales: Peterson, Joshua C., Wisse, Lambertus J., Wirokromo, Valerie, van Herwaarden, Tessa, Smits, Anke M., Gittenberger-de Groot, Adriana C., Goumans, Marie-José T. H., VanMunsteren, J. Conny, Jongbloed, Monique R. M., DeRuiter, Marco C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541347/
https://www.ncbi.nlm.nih.gov/pubmed/32801116
http://dx.doi.org/10.1242/dmm.044990

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