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An untargeted metabolomics strategy to measure differences in metabolite uptake and excretion by mammalian cell lines
INTRODUCTION: It is widely but erroneously believed that drugs get into cells by passing through the phospholipid bilayer portion of the plasma and other membranes. Much evidence shows, however, that this is not the case, and that drugs cross biomembranes by hitchhiking on transporters for other nat...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541387/ https://www.ncbi.nlm.nih.gov/pubmed/33026554 http://dx.doi.org/10.1007/s11306-020-01725-8 |