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Decreased Mitochondrial Function, Biogenesis, and Degradation in Peripheral Blood Mononuclear Cells from Amyotrophic Lateral Sclerosis Patients as a Potential Tool for Biomarker Research
Amyotrophic lateral sclerosis (ALS) is a multifactorial and progressive neurodegenerative disease of unknown etiology. Due to ALS’s unpredictable onset and progression rate, the search for biomarkers that allow the detection and tracking of its development and therapeutic efficacy would be of signif...
Autores principales: | Araujo, Beatriz Grisolia, Souza e Silva, Luiz Felipe, de Barros Torresi, Jorge Luiz, Siena, Amanda, Valerio, Berenice Cataldo Oliveira, Brito, Mariana Dutra, Rosenstock, Tatiana Rosado |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541388/ https://www.ncbi.nlm.nih.gov/pubmed/32840822 http://dx.doi.org/10.1007/s12035-020-02059-1 |
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