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Many small steps towards a COVID-19 drug
A large-scale screening campaign has yielded dozens of crystal structures of small molecule fragments that bind to the main protease of SARS-CoV-2. The global research community is encouraged to pursue these as drug discovery starting points for COVID-19.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541474/ https://www.ncbi.nlm.nih.gov/pubmed/33028832 http://dx.doi.org/10.1038/s41467-020-18710-3 |
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author | Erlanson, Daniel A. |
author_facet | Erlanson, Daniel A. |
author_sort | Erlanson, Daniel A. |
collection | PubMed |
description | A large-scale screening campaign has yielded dozens of crystal structures of small molecule fragments that bind to the main protease of SARS-CoV-2. The global research community is encouraged to pursue these as drug discovery starting points for COVID-19. |
format | Online Article Text |
id | pubmed-7541474 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-75414742020-10-19 Many small steps towards a COVID-19 drug Erlanson, Daniel A. Nat Commun Comment A large-scale screening campaign has yielded dozens of crystal structures of small molecule fragments that bind to the main protease of SARS-CoV-2. The global research community is encouraged to pursue these as drug discovery starting points for COVID-19. Nature Publishing Group UK 2020-10-07 /pmc/articles/PMC7541474/ /pubmed/33028832 http://dx.doi.org/10.1038/s41467-020-18710-3 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Comment Erlanson, Daniel A. Many small steps towards a COVID-19 drug |
title | Many small steps towards a COVID-19 drug |
title_full | Many small steps towards a COVID-19 drug |
title_fullStr | Many small steps towards a COVID-19 drug |
title_full_unstemmed | Many small steps towards a COVID-19 drug |
title_short | Many small steps towards a COVID-19 drug |
title_sort | many small steps towards a covid-19 drug |
topic | Comment |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541474/ https://www.ncbi.nlm.nih.gov/pubmed/33028832 http://dx.doi.org/10.1038/s41467-020-18710-3 |
work_keys_str_mv | AT erlansondaniela manysmallstepstowardsacovid19drug |