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Palaeoproteomic analysis of Pleistocene cave hyenas from east Asia
The spotted hyena (Crocuta crocuta) is the only extant species of the genus Crocuta, which once occupied a much wider range during the Pliocene and Pleistocene. However, its origin and evolutionary history is somewhat contentious due to discordances between morphological, nuclear, and mitochondrial...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541484/ https://www.ncbi.nlm.nih.gov/pubmed/33028848 http://dx.doi.org/10.1038/s41598-020-73542-x |
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author | Rao, Huiyun Yang, Yimin Liu, Jinyi Westbury, Michael V. Zhang, Chi Shao, Qingfeng |
author_facet | Rao, Huiyun Yang, Yimin Liu, Jinyi Westbury, Michael V. Zhang, Chi Shao, Qingfeng |
author_sort | Rao, Huiyun |
collection | PubMed |
description | The spotted hyena (Crocuta crocuta) is the only extant species of the genus Crocuta, which once occupied a much wider range during the Pliocene and Pleistocene. However, its origin and evolutionary history is somewhat contentious due to discordances between morphological, nuclear, and mitochondrial data. Due to the limited molecular data from east Asian Crocuta, also known as cave hyena, and the difficulty of extracting ancient DNA from this area, here we present proteomic analysis of cave hyenas from three locations in northern China. This marks the first proteomic data generated from cave hyenas, adding new molecular data to the east Asian populations. Phylogenetic analysis based on these protein sequences reveals two different groups of cave hyenas in east Asia, one of which could not be distinguished from modern spotted hyenas from northern Africa, tentatively the result of previously suggested gene flow between these lineages. With developments of instrumentation and analytical methods, proteomics holds promising potential for molecular phylogenetic reconstructions of ancient fauna previously thought to be unreachable using ancient DNA. |
format | Online Article Text |
id | pubmed-7541484 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-75414842020-10-08 Palaeoproteomic analysis of Pleistocene cave hyenas from east Asia Rao, Huiyun Yang, Yimin Liu, Jinyi Westbury, Michael V. Zhang, Chi Shao, Qingfeng Sci Rep Article The spotted hyena (Crocuta crocuta) is the only extant species of the genus Crocuta, which once occupied a much wider range during the Pliocene and Pleistocene. However, its origin and evolutionary history is somewhat contentious due to discordances between morphological, nuclear, and mitochondrial data. Due to the limited molecular data from east Asian Crocuta, also known as cave hyena, and the difficulty of extracting ancient DNA from this area, here we present proteomic analysis of cave hyenas from three locations in northern China. This marks the first proteomic data generated from cave hyenas, adding new molecular data to the east Asian populations. Phylogenetic analysis based on these protein sequences reveals two different groups of cave hyenas in east Asia, one of which could not be distinguished from modern spotted hyenas from northern Africa, tentatively the result of previously suggested gene flow between these lineages. With developments of instrumentation and analytical methods, proteomics holds promising potential for molecular phylogenetic reconstructions of ancient fauna previously thought to be unreachable using ancient DNA. Nature Publishing Group UK 2020-10-07 /pmc/articles/PMC7541484/ /pubmed/33028848 http://dx.doi.org/10.1038/s41598-020-73542-x Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Rao, Huiyun Yang, Yimin Liu, Jinyi Westbury, Michael V. Zhang, Chi Shao, Qingfeng Palaeoproteomic analysis of Pleistocene cave hyenas from east Asia |
title | Palaeoproteomic analysis of Pleistocene cave hyenas from east Asia |
title_full | Palaeoproteomic analysis of Pleistocene cave hyenas from east Asia |
title_fullStr | Palaeoproteomic analysis of Pleistocene cave hyenas from east Asia |
title_full_unstemmed | Palaeoproteomic analysis of Pleistocene cave hyenas from east Asia |
title_short | Palaeoproteomic analysis of Pleistocene cave hyenas from east Asia |
title_sort | palaeoproteomic analysis of pleistocene cave hyenas from east asia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541484/ https://www.ncbi.nlm.nih.gov/pubmed/33028848 http://dx.doi.org/10.1038/s41598-020-73542-x |
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