Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis

Epilepsy is one of the most common neurological disorders, yet its pathophysiology is poorly understood due to the high complexity of affected neuronal circuits. To identify dysfunctional neuronal subtypes underlying seizure activity in the human brain, we have performed single-nucleus transcriptomi...

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Detalles Bibliográficos
Autores principales: Pfisterer, Ulrich, Petukhov, Viktor, Demharter, Samuel, Meichsner, Johanna, Thompson, Jonatan J., Batiuk, Mykhailo Y., Martinez, Andrea Asenjo, Vasistha, Navneet A., Thakur, Ashish, Mikkelsen, Jens, Adorjan, Istvan, Pinborg, Lars H., Pers, Tune H., von Engelhardt, Jakob, Kharchenko, Peter V., Khodosevich, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541486/
https://www.ncbi.nlm.nih.gov/pubmed/33028830
http://dx.doi.org/10.1038/s41467-020-18752-7

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