Wnt antagonist FRZB is a muscle biomarker of denervation atrophy in amyotrophic lateral sclerosis

Skeletal muscle and the neuromuscular junction are the earliest sites to manifest pathological changes in amyotrophic lateral sclerosis (ALS). Based on prior studies, we have identified a molecular signature in muscle that develops early in ALS and parallels disease progression. This signature repre...

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Detalles Bibliográficos
Autores principales: Kwan, Thaddaeus, Kazamel, Mohamed, Thoenes, Kristina, Si, Ying, Jiang, Nan, King, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541525/
https://www.ncbi.nlm.nih.gov/pubmed/33028902
http://dx.doi.org/10.1038/s41598-020-73845-z

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