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Tankyrase inhibitor XAV-939 enhances osteoblastogenesis and mineralization of human skeletal (mesenchymal) stem cells

Tankyrase is part of poly (ADP-ribose) polymerase superfamily required for numerous cellular and molecular processes. Tankyrase inhibition negatively regulates Wnt pathway. Thus, Tankyrase inhibitors have been extensively investigated for the treatment of clinical conditions associated with activate...

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Detalles Bibliográficos
Autores principales: Almasoud, Nuha, Binhamdan, Sarah, Younis, Ghaydaa, Alaskar, Hanouf, Alotaibi, Amal, Manikandan, Muthurangan, Alfayez, Musaad, Kassem, Moustapha, AlMuraikhi, Nihal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541626/
https://www.ncbi.nlm.nih.gov/pubmed/33028869
http://dx.doi.org/10.1038/s41598-020-73439-9