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Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Regulates Neurite Outgrowth Through the Activation of Akt/mTOR and Erk/mTOR Signaling Pathways

Neurite outgrowth is essential for brain development and the recovery of brain injury and neurodegenerative diseases. In this study, we examined the role of the neurotrophic factor MANF in regulating neurite outgrowth. We generated MANF knockout (KO) neuro2a (N2a) cell lines using clustered regularl...

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Detalles Bibliográficos
Autores principales:	Wen, Wen, Wang, Yongchao, Li, Hui, Xu, Hong, Xu, Mei, Frank, Jacqueline A., Ma, Murong, Luo, Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541815/ https://www.ncbi.nlm.nih.gov/pubmed/33071755 http://dx.doi.org/10.3389/fnmol.2020.560020

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