Cargando…

Complement-Mediated Microglial Phagocytosis and Pathological Changes in the Development and Degeneration of the Visual System

The focus of this review is the role of complement-mediated phagocytosis in retinal and neurological diseases affecting the visual system. Complement activation products opsonize synaptic material on neurons for phagocytic removal, which is a normal physiological process during development, but a pa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Borucki, Davis M., Toutonji, Amer, Couch, Christine, Mallah, Khalil, Rohrer, Baerbel, Tomlinson, Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541817/ https://www.ncbi.nlm.nih.gov/pubmed/33072106 http://dx.doi.org/10.3389/fimmu.2020.566892

Ejemplares similares

Anti-inflammatory and Neuroprotective Agents in Clinical Trials for CNS Disease and Injury: Where Do We Go From Here?
por: Mallah, Khalil, et al.
Publicado: (2020)

Evaluating the comorbidities of age and cigarette smoking on stroke outcomes in the context of anti-complement mitigation strategies
por: Couch, Christine, et al.
Publicado: (2023)

Mass cytometric analysis of the immune cell landscape after traumatic brain injury elucidates the role of complement and complement receptors in neurologic outcomes
por: Toutonji, Amer, et al.
Publicado: (2023)

Complement mediates neuroinflammation and cognitive decline at extended chronic time points after traumatic brain injury
por: Mallah, Khalil, et al.
Publicado: (2021)

A Role of Complement in the Pathogenic Sequelae of Mouse Neonatal Germinal Matrix Hemorrhage
por: Alshareef, Mohammed, et al.
Publicado: (2022)

A Role for P-selectin and Complement in the Pathological Sequelae of Germinal Matrix Hemorrhage
por: Hatchell, Devin, et al.
Publicado: (2023)

A role for P-selectin and complement in the pathological sequelae of germinal matrix hemorrhage
por: Hatchell, Devin, et al.
Publicado: (2023)

The Role of Microglial Phagocytosis in Ischemic Stroke
por: Jia, Junqiu, et al.
Publicado: (2022)

Chronic complement dysregulation drives neuroinflammation after traumatic brain injury: a transcriptomic study
por: Toutonji, Amer, et al.
Publicado: (2021)

Interrogation of human microglial phagocytosis by CRISPR genome editing
por: Chang, Jason Cheng-Yu, et al.
Publicado: (2023)

Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration
por: Zhao, Lian, et al.
Publicado: (2015)

Commentary: CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
por: Wei, Penghui, et al.
Publicado: (2019)

The Complement System Is Essential for the Phagocytosis of Mesenchymal Stromal Cells by Monocytes
por: Gavin, Caroline, et al.
Publicado: (2019)

Central nervous system diseases related to pathological microglial phagocytosis
por: Wang, Ke, et al.
Publicado: (2021)

LRPAP1 is released from activated microglia and inhibits microglial phagocytosis and amyloid beta aggregation
por: Reid, Kyle M., et al.
Publicado: (2023)

Complement Receptor-Mediated Phagocytosis Induces Proinflammatory Cytokine Production in Murine Macrophages
por: Acharya, Durga, et al.
Publicado: (2020)

REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis
por: Griffin, Percy, et al.
Publicado: (2020)

Complement in the Homeostatic and Ischemic Brain
por: Alawieh, Ali, et al.
Publicado: (2015)

Monoclonal antibodies effectively potentiate complement activation and phagocytosis of Staphylococcus epidermidis in neonatal human plasma
por: de Vor, Lisanne, et al.
Publicado: (2022)

Microglial trogocytosis and the complement system regulate axonal pruning in vivo
por: Lim, Tony KY, et al.
Publicado: (2021)

Microglia Inhibition Delays Retinal Degeneration Due to MerTK Phagocytosis Receptor Deficiency
por: Lew, Deborah S., et al.
Publicado: (2020)

Complementing regeneration
por: Alawieh, Ali, et al.
Publicado: (2015)

Bacillus anthracis Poly-γ-D-Glutamate Capsule Inhibits Opsonic Phagocytosis by Impeding Complement Activation
por: Sharma, Shikhar, et al.
Publicado: (2020)

CRP Enhances the Innate Killing Mechanisms Phagocytosis and ROS Formation in a Conformation and Complement-Dependent Manner
por: Zeller, Johannes, et al.
Publicado: (2021)

Absent in melanoma 2 mediates aging‐related cognitive dysfunction by acting on complement‐dependent microglial phagocytosis
por: Ye, Lei, et al.
Publicado: (2023)

Reticulocalbin-1 Facilitates Microglial Phagocytosis
por: Ding, Ying, et al.
Publicado: (2015)

TMEM16F Aggravates Neuronal Loss by Mediating Microglial Phagocytosis of Neurons in a Rat Experimental Cerebral Ischemia and Reperfusion Model
por: Zhang, Yijie, et al.
Publicado: (2020)

The role of complement in nonalcoholic fatty liver disease
por: Guo, Zhenya, et al.
Publicado: (2022)

Qki is an essential regulator of microglial phagocytosis in demyelination
por: Ren, Jiangong, et al.
Publicado: (2020)

Regulatable Complement Inhibition of the Alternative Pathway Mitigates Wet Age-Related Macular Degeneration Pathology in a Mouse Model
por: Parsons, Nathaniel B., et al.
Publicado: (2023)

ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo
por: Barcia, Carlos, et al.
Publicado: (2012)

Modulation of the Complement System by Neoplastic Disease of the Central Nervous System
por: Yarmoska, Steven K., et al.
Publicado: (2021)

Editorial: New insights into the role of complement system in liver diseases
por: Guo, Zhenya, et al.
Publicado: (2023)

Harnessing and Enhancing Macrophage Phagocytosis for Cancer Therapy
por: Chen, Siqi, et al.
Publicado: (2021)

Binding of von Willebrand Factor to Complement C1q Decreases the Phagocytosis of Cholesterol Crystals and Subsequent IL-1 Secretion in Macrophages
por: Donat, Claudia, et al.
Publicado: (2019)

Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction
por: Konishi, Hiroyuki, et al.
Publicado: (2020)

Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During Francisella tularensis Phagocytosis by Human Mononuclear Phagocytes
por: Hoang, Ky V., et al.
Publicado: (2018)

Complement receptor-3 negatively regulates the phagocytosis of degenerated myelin through tyrosine kinase Syk and cofilin
por: Hadas, Smadar, et al.
Publicado: (2012)

Microglial burden, activation and dystrophy patterns in frontotemporal lobar degeneration
por: Woollacott, Ione O. C., et al.
Publicado: (2020)

LRRK2 kinase inhibition prevents pathological microglial phagocytosis in response to HIV-1 Tat protein
por: Marker, Daniel F, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_rld7k6i7ngkgm158h2ot6j8aa0