Cargando…

Clinical Value of NOTCH1 Mutations Detection among Chronic Lymphocytic Leukemia Patients

BACKGROUND: The data about the clinical impact of NOTCH1 mutations among Egyptians B – cell chronic lymphocytic patients is not previously identified. We herein, evaluate the prevalence and the prognostic significance of neurogenic locus notch homolog protein-1 (NOTCH1) mutations in B- cell lymphocy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Are, Salah, El-Agdar, Mohamed, Salama, Osama, Abouzeid, Tarek, Sabry, Mohamed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541881/ https://www.ncbi.nlm.nih.gov/pubmed/32458636 http://dx.doi.org/10.31557/APJCP.2020.21.5.1295

Ejemplares similares

NOTCH-1 Gene Mutations Influence Survival in Acute Myeloid Leukemia Patients
por: Aref, Salah, et al.
Publicado: (2020)

Prognostic Value of Plasma miR-29a Evaluation in Chronic Lymphocytic Leukemia Patients
por: Aref, Salah, et al.
Publicado: (2023)

Prognostic Value of CD200 Expression and Soluble CTLA-4 Concentrations in Intermediate and High-Risk Myelodysplastic Syndrome Patients
por: Aref, Salah, et al.
Publicado: (2020)

Prognostic value of CD25/CD123 pattern of expression in acute myeloid leukemia patients with normal cytogenetic
por: Aref, Salah, et al.
Publicado: (2020)

Evaluation of Cortactin and HS1 Genes Expression: New Players in Adult B-Cell Acute Lymphoblastic leukemia
por: Aref, Salah, et al.
Publicado: (2021)

Implication of Dynamin-2 (DNM2) Mutations in Adult T-cell Acute Lymphoblastic Leukemia
por: Sobh, Marwa, et al.
Publicado: (2023)

Prognostic Value of Serum CD200 Concentrations in Chronic Lymphocytic Leukemia
por: Aref, Salah, et al.
Publicado: (2023)

Clinical Impact of CD25/CD123 Coexpression in Adult B-Cell Acute Lymphoblastic Leukemia Patients
por: Aref, Salah, et al.
Publicado: (2020)

Multiple Mechanisms of NOTCH1 Activation in Chronic Lymphocytic Leukemia: NOTCH1 Mutations and Beyond
por: Pozzo, Federico, et al.
Publicado: (2022)

NOTCH1 mutations influence survival in chronic lymphocytic leukemia patients
por: Willander, Kerstin, et al.
Publicado: (2013)

NOTCH1 Aberrations in Chronic Lymphocytic Leukemia
por: Rosati, Emanuela, et al.
Publicado: (2018)

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation
por: Fabbri, Giulia, et al.
Publicado: (2011)

Droplet digital PCR analysis of NOTCH1 gene mutations in chronic lymphocytic leukemia
por: Minervini, Angela, et al.
Publicado: (2016)

NOTCH1 Activation Negatively Impacts on Chronic Lymphocytic Leukemia Outcome and Is Not Correlated to the NOTCH1 and IGHV Mutational Status
por: Baldoni, Stefano, et al.
Publicado: (2021)

The p53 transcriptional pathway is preserved in ATM(mutated) and NOTCH1(mutated) chronic lymphocytic leukemias
por: Athanasakis, Emmanouil, et al.
Publicado: (2014)

Constitutive activation of NF-κB signaling by NOTCH1 mutations in chronic lymphocytic leukemia
por: XU, ZHEN-SHU, et al.
Publicado: (2015)

A Novel Assay for the Identification of NOTCH1 PEST Domain Mutations in Chronic Lymphocytic Leukemia
por: Campregher, Paulo Vidal, et al.
Publicado: (2016)

The Predominant Prognostic Significance of NOTCH1 Mutation Defined by Emulsion PCR in Chronic Lymphocytic Leukemia
por: Skórka, Katarzyna, et al.
Publicado: (2021)

Prognostic Value of TLE1 Gene Expression in Patients with T-cell Acute Lymphoblastic Leukemia
por: Aref, Salah, et al.
Publicado: (2021)

PB1946: NOTCH PATHWAY MUTATION CONTRIBUTES TO INFERIOR PROGNOSIS IN HBV-INFECTED CHRONIC LYMPHOCYTIC LEUKEMIA
por: Shang, Chunyu, et al.
Publicado: (2023)

Wilms Tumor 1 Gene Mutations in Patients with Cytogenetically Normal Acute Myeloid Leukemia
por: Aref, Salah, et al.
Publicado: (2014)

Clinical Implication of DNMT3A and TET2 Genes Mutations in Cytogenetically Normal Acute Myeloid Leukemia
por: Aref, Salah, et al.
Publicado: (2022)

Non-coding NOTCH1 mutations in chronic lymphocytic leukemia; their clinical impact in the UK CLL4 trial
por: Larrayoz, M, et al.
Publicado: (2017)

PB1871: PROGNOSTIC SIGNIFICANCE OF THE NOTCH1 GENE MUTATION AND OTHER LABORATORY FACTORS IN CHRONIC LYMPHOCYTIC LEUKEMIA
por: Krauchanka, D., et al.
Publicado: (2022)

NOTCH1-mutated chronic lymphocytic leukemia displays high endoplasmic reticulum stress response with druggable potential
por: Silva Barcelos, Estevão Carlos, et al.
Publicado: (2023)

NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells
por: Di Ianni, Mauro, et al.
Publicado: (2018)

Relapsed chronic lymphocytic leukemia with a cardiac mass: A case report
por: Mahmoud, Amir A., et al.
Publicado: (2023)

NOTCH1 mutation and its prognostic significance in Chinese chronic lymphocytic leukemia: a retrospective study of 317 cases
por: Zou, Yixin, et al.
Publicado: (2018)

Prognostic correlation of NOTCH1 and SF3B1 mutations with chromosomal abnormalities in chronic lymphocytic leukemia patients
por: Sadria, Reza, et al.
Publicado: (2022)

ITGA4 gene methylation status in chronic lymphocytic leukemia
por: Attia, Hanaa RM, et al.
Publicado: (2020)

Artificial Intelligence Enhances Diagnostic Flow Cytometry Workflow in the Detection of Minimal Residual Disease of Chronic Lymphocytic Leukemia
por: Salama, Mohamed E., et al.
Publicado: (2022)

Mutational landscape and underlying mutational processes in chronic lymphocytic leukemia
por: Kasar, S., et al.
Publicado: (2016)

Interferon regulatory factor 4 attenuates Notch signaling to suppress the development of chronic lymphocytic leukemia
por: Shukla, Vipul, et al.
Publicado: (2016)

Pleurisy as a Sign of Chronic Lymphocytic Leukemia
por: Thouil, Afaf, et al.
Publicado: (2023)

APOBEC3 signature mutations in chronic lymphocytic leukemia
por: Rebhandl, S, et al.
Publicado: (2014)

Overview of non‐coding mutations in chronic lymphocytic leukemia
por: Spina, Valeria, et al.
Publicado: (2019)

Leukemia Cutis as an Early Presentation or Relapsing Manifestation of Chronic Lymphocytic Leukemia (CLL)
por: Aldapt, Mahmood B, et al.
Publicado: (2021)

Impaired nodal shrinkage and apoptosis define the independent adverse outcome of NOTCH1 mutated patients under ibrutinib therapy in chronic lymphocytic leukemia
por: Del Poeta, Giovanni, et al.
Publicado: (2020)

SF3B1-mutated chronic lymphocytic leukemia shows evidence of NOTCH1 pathway activation including CD20 downregulation
por: Pozzo, Federico, et al.
Publicado: (2020)

Bepridil exhibits anti‐leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia
por: Baldoni, Stefano, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ojdi06ad47n77aujk6b3hbsfve