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Structural Recognition and Binding Pattern Analysis of Human Topoisomerase II Alpha with Steroidal Drugs: In Silico Study to Switchover the Cancer Treatment
BACKGROUND AND OBJECTIVE: Topoisomerase TOP-IIA (TTOP-IIA) is widely used as a significant target for cancer therapeutics because of its involvement in cell proliferation. Steroidal drugs have been suggested for breast cancer treatment as aromatase enzymes inhibitors . TTOP-IIA inhibitors can be use...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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West Asia Organization for Cancer Prevention
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541882/ https://www.ncbi.nlm.nih.gov/pubmed/32458643 http://dx.doi.org/10.31557/APJCP.2020.21.5.1349 |