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Occupational Exposure and Risk Assessment of Formaldehyde in the Pathology Departments of Hospitals

BACKGROUND AND OBJECTIVE: Exposure to formaldehyde has adverse effects on health both acutely and over the long term (e.g., carcinogenicity). The substance is widely used in pathology and histology departments. This study focused on cancer risk of formaldehyde in pathology department of five hospita...

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Autores principales: Yahyaei, Elham, Majlesi, Behzad, Naimi joubani, Mohammad, Pourbakhshi, Yasaman, Ghiyasi, Samira, Jamshidi Rastani, Mehdi, Heidari, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541887/
https://www.ncbi.nlm.nih.gov/pubmed/32458637
http://dx.doi.org/10.31557/APJCP.2020.21.5.1303
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author Yahyaei, Elham
Majlesi, Behzad
Naimi joubani, Mohammad
Pourbakhshi, Yasaman
Ghiyasi, Samira
Jamshidi Rastani, Mehdi
Heidari, Mahmoud
author_facet Yahyaei, Elham
Majlesi, Behzad
Naimi joubani, Mohammad
Pourbakhshi, Yasaman
Ghiyasi, Samira
Jamshidi Rastani, Mehdi
Heidari, Mahmoud
author_sort Yahyaei, Elham
collection PubMed
description BACKGROUND AND OBJECTIVE: Exposure to formaldehyde has adverse effects on health both acutely and over the long term (e.g., carcinogenicity). The substance is widely used in pathology and histology departments. This study focused on cancer risk of formaldehyde in pathology department of five hospitals in Rasht. MATERIALS AND METHODS: Sampling and determination of formaldehyde in pathology department were carried out based on the NIOSH method of 3500. The working condition and working environment were investigated and a semi quantitative risk assessment were used to health risk assessment of formaldehyde and The individual lifetime cancer probability, which is defined as the increase in the probability of developing cancer during continuous exposure to an air pollutant were used to assess health risks with formaldehyde. RESULTS: The results showed that the exposure level of all subjects were higher than the Occupational Exposure Limit for 8 hours exposure time of formaldehyde. However, in the five occupational groups, the highest weekly exposure index was observed for the Lab Technicians (0.664 ppm) at Hospital no. 5, which could have been due to more daily working hours at this sampling site and a lack of adequate ventilation. The formaldehyde concentration was in the 0.0192 to 0.326 ppm ranges for five hospital pathology departments. The cancer risk ranged from 9.52×10(-5) to 1.53×10(-3), and it was greater than the WHO acceptable cancer risk level. CONCLUSIONS: The results of the risk assessments can be used for managing the chemical exposure of allocated resources for defining control actions. This process plays an important role in reducing the level of exposure to formaldehyde in pathology departments.
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spelling pubmed-75418872020-10-14 Occupational Exposure and Risk Assessment of Formaldehyde in the Pathology Departments of Hospitals Yahyaei, Elham Majlesi, Behzad Naimi joubani, Mohammad Pourbakhshi, Yasaman Ghiyasi, Samira Jamshidi Rastani, Mehdi Heidari, Mahmoud Asian Pac J Cancer Prev Research Article BACKGROUND AND OBJECTIVE: Exposure to formaldehyde has adverse effects on health both acutely and over the long term (e.g., carcinogenicity). The substance is widely used in pathology and histology departments. This study focused on cancer risk of formaldehyde in pathology department of five hospitals in Rasht. MATERIALS AND METHODS: Sampling and determination of formaldehyde in pathology department were carried out based on the NIOSH method of 3500. The working condition and working environment were investigated and a semi quantitative risk assessment were used to health risk assessment of formaldehyde and The individual lifetime cancer probability, which is defined as the increase in the probability of developing cancer during continuous exposure to an air pollutant were used to assess health risks with formaldehyde. RESULTS: The results showed that the exposure level of all subjects were higher than the Occupational Exposure Limit for 8 hours exposure time of formaldehyde. However, in the five occupational groups, the highest weekly exposure index was observed for the Lab Technicians (0.664 ppm) at Hospital no. 5, which could have been due to more daily working hours at this sampling site and a lack of adequate ventilation. The formaldehyde concentration was in the 0.0192 to 0.326 ppm ranges for five hospital pathology departments. The cancer risk ranged from 9.52×10(-5) to 1.53×10(-3), and it was greater than the WHO acceptable cancer risk level. CONCLUSIONS: The results of the risk assessments can be used for managing the chemical exposure of allocated resources for defining control actions. This process plays an important role in reducing the level of exposure to formaldehyde in pathology departments. West Asia Organization for Cancer Prevention 2020-05 /pmc/articles/PMC7541887/ /pubmed/32458637 http://dx.doi.org/10.31557/APJCP.2020.21.5.1303 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Yahyaei, Elham
Majlesi, Behzad
Naimi joubani, Mohammad
Pourbakhshi, Yasaman
Ghiyasi, Samira
Jamshidi Rastani, Mehdi
Heidari, Mahmoud
Occupational Exposure and Risk Assessment of Formaldehyde in the Pathology Departments of Hospitals
title Occupational Exposure and Risk Assessment of Formaldehyde in the Pathology Departments of Hospitals
title_full Occupational Exposure and Risk Assessment of Formaldehyde in the Pathology Departments of Hospitals
title_fullStr Occupational Exposure and Risk Assessment of Formaldehyde in the Pathology Departments of Hospitals
title_full_unstemmed Occupational Exposure and Risk Assessment of Formaldehyde in the Pathology Departments of Hospitals
title_short Occupational Exposure and Risk Assessment of Formaldehyde in the Pathology Departments of Hospitals
title_sort occupational exposure and risk assessment of formaldehyde in the pathology departments of hospitals
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541887/
https://www.ncbi.nlm.nih.gov/pubmed/32458637
http://dx.doi.org/10.31557/APJCP.2020.21.5.1303
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