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Prokineticin Receptor Inhibition With PC1 Protects Mouse Primary Sensory Neurons From Neurotoxic Effects of Chemotherapeutic Drugs in vitro

Neurotoxicity is a common side effect of chemotherapeutics that often leads to the development of chemotherapy-induced peripheral neuropathy (CIPN). The peptide Prokineticin 2 (PK2) has a key role in experimental models of CIPN and can be considered an insult-inducible endangering mediator. Since pr...

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Detalles Bibliográficos
Autores principales: Moschetti, Giorgia, Kalpachidou, Theodora, Amodeo, Giada, Lattanzi, Roberta, Sacerdote, Paola, Kress, Michaela, Franchi, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541916/
https://www.ncbi.nlm.nih.gov/pubmed/33072073
http://dx.doi.org/10.3389/fimmu.2020.02119

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