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Prokineticin Receptor Inhibition With PC1 Protects Mouse Primary Sensory Neurons From Neurotoxic Effects of Chemotherapeutic Drugs in vitro
Neurotoxicity is a common side effect of chemotherapeutics that often leads to the development of chemotherapy-induced peripheral neuropathy (CIPN). The peptide Prokineticin 2 (PK2) has a key role in experimental models of CIPN and can be considered an insult-inducible endangering mediator. Since pr...
Autores principales: | Moschetti, Giorgia, Kalpachidou, Theodora, Amodeo, Giada, Lattanzi, Roberta, Sacerdote, Paola, Kress, Michaela, Franchi, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541916/ https://www.ncbi.nlm.nih.gov/pubmed/33072073 http://dx.doi.org/10.3389/fimmu.2020.02119 |
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