Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion

Myeloid cell heterogeneity remains poorly studied in breast cancer, and particularly in premalignancy. Here, we used single cell RNA sequencing to characterize macrophage diversity in mouse pre-invasive lesions as compared to lesions undergoing localized invasion. Several subpopulations of macrophag...

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Detalles Bibliográficos
Autores principales: Ibrahim, Ayman M., Moss, Matthew A., Gray, Zane, Rojo, Michelle D., Burke, Caitlin M., Schwertfeger, Kathryn L., dos Santos, Camila O., Machado, Heather L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541939/
https://www.ncbi.nlm.nih.gov/pubmed/33072601
http://dx.doi.org/10.3389/fonc.2020.569985

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