Cargando…

High Cell-Free DNA Levels in Cerebrospinal Fluid Predict Leptomeningeal Seeding of Hematologic Malignancy

BACKGROUND AND PURPOSE: The main difficulty when diagnosing leptomeningeal metastases (LMSs) is the low sensitivity of cytology. Cancer cells release cell-free DNA (cfDNA) during proliferation and apoptosis, and so we analyzed the cfDNA level as a biomarker for LMSs in hematologic malignancy. METHOD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Eun Young, Lee, Soon-Tae, Kim, Young-Sook, Byun, Ja Min, Hong, Junshik, Shin, Dong-Yeop, Koh, Youngil, Kim, Inho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Neurological Association 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541998/ https://www.ncbi.nlm.nih.gov/pubmed/33029963 http://dx.doi.org/10.3988/jcn.2020.16.4.581

Ejemplares similares

Depletion of nerve growth factor in chemotherapy-induced peripheral neuropathy associated with hematologic malignancies
por: Youk, Jeonghwan, et al.
Publicado: (2017)

Distinct predictive impact of FISH abnormality in proteasome inhibitors and immunomodulatory agents response: redefining high‐risk multiple myeloma in Asian patients
por: Byun, Ja Min, et al.
Publicado: (2018)

Allogeneic Stem Cell Transplantation in Relapsed/Refractory Multiple Myeloma Treatment: Is It Still Relevant?
por: Park, Hyunkyung, et al.
Publicado: (2020)

Busulfan plus melphalan versus melphalan alone conditioning regimen after bortezomib based triplet induction chemotherapy for patients with newly diagnosed multiple myeloma
por: Park, Songyi, et al.
Publicado: (2021)

Association between preconditioning absolute lymphocyte count and transplant outcomes in patients undergoing matched unrelated donor allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning and anti-thymocyte globulin
por: Seo, Jeongmin, et al.
Publicado: (2021)

Romiplostim plus danazol as salvage treatment for eltrombopag refractory immune thrombocytopenia: a retrospective pilot study
por: Nam, Chang Hyun, et al.
Publicado: (2021)

Serum Erythropoietin level in anemia of elderly with unclear etiology
por: Seong, Ju Yong, et al.
Publicado: (2023)

Strong association between herpes simplex virus-1 and chemotherapy-induced oral mucositis in patients with hematologic malignancies
por: Hong, Junshik, et al.
Publicado: (2020)

Reduced-intensity conditioning versus myeloablative conditioning allogeneic stem cell transplantation for patients with myelofibrosis
por: Kim, Dong Hyun, et al.
Publicado: (2022)

Comparison of the effect of DLI according to cell sources in relapsed AML after allogeneic stem cell transplantation
por: Park, Woochan, et al.
Publicado: (2023)

Eltrombopag for Post-Transplant Poor Graft Function in East Asian Patients
por: Ahn, Hyun Jin, et al.
Publicado: (2022)

Cyclophosphamide addition to pomalidomide/dexamethasone is not necessarily associated with universal benefits in RRMM
por: Park, Hyunkyung, et al.
Publicado: (2022)

Benefits of Thromboelastography and Thrombin Generation Assay for Bleeding Prediction in Patients With Thrombocytopenia or Hematologic Malignancies
por: Kim, Seon Young, et al.
Publicado: (2017)

Incidence, characteristics and risk factors of thromboembolic events in East Asian patients with BCR-ABL1 negative myeloproliferative neoplasms
por: Kim, Jinyong, et al.
Publicado: (2021)

Should patients receive consolidation chemotherapy before reduced intensity allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia in first complete remission?
por: Byun, Ja Min, et al.
Publicado: (2021)

Diagnostic Value of Cerebrospinal Fluid Level of Carcinoembryonic Antigen in Patients with Leptomeningeal Carcinomatous Metastasis
por: Kang, Sung Jin, et al.
Publicado: (2010)

Clinical outcome of cerebrospinal fluid shunts in patients with leptomeningeal carcinomatosis
por: Kim, Hye Seon, et al.
Publicado: (2019)

Leptomeningeal Metastasis: The Role of Cerebrospinal Fluid Diagnostics
por: Bönig, Lena, et al.
Publicado: (2019)

P1157: PHASE II STUDY OF GLOFITAMAB, POSELTINIB AND LENALIDOMIDE IN PATIENTS WITH RELAPSED/REFRACTORY DIFFUSE B CELL LYMPHOMAS
por: Min Byun, Ja, et al.
Publicado: (2023)

Leptomeningeal Seeding in Choroidal Melanoma after Enucleation Surgery
por: Kim, Tae Hwan, et al.
Publicado: (2020)

Author Correction: Helicobacter pylori eradication affects platelet count recovery in immune thrombocytopenia
por: Lee, Ayoung, et al.
Publicado: (2020)

Helicobacter pylori eradication affects platelet count recovery in immune thrombocytopenia
por: Lee, Ayoung, et al.
Publicado: (2020)

Better treatment outcomes in patients with actively treated therapy-related myeloid neoplasms harboring a normal karyotype
por: Kim, Sang-A, et al.
Publicado: (2018)

Detection of Leptomeningeal Disease Using Cell-Free DNA From Cerebrospinal Fluid
por: White, Michael D., et al.
Publicado: (2021)

Diagnostic and prognostic values of cerebrospinal fluid CYFRA 21-1 in patients with leptomeningeal carcinomatosis
por: Hyun, Jae-Won, et al.
Publicado: (2017)

Concomitant ruxolitinib with cytarabine-based induction chemotherapy in secondary acute myeloid leukemia evolving from myeloproliferative neoplasm
por: Kim, Dong Hyun, et al.
Publicado: (2023)

Immunohistochemical analysis of the cerebrospinal fluid for carcinomatous and lymphomatous leptomeningitis.
por: Hovestadt, A., et al.
Publicado: (1990)

Cerebrospinal Fluid Penetrance of Daratumumab in Leptomeningeal Multiple Myeloma
por: Zajec, Marina, et al.
Publicado: (2020)

Cerebrospinal fluid metabolomic profiles can discriminate patients with leptomeningeal carcinomatosis from patients at high risk for leptomeningeal metastasis
por: Yoo, Byong Chul, et al.
Publicado: (2017)

Mannan-binding lectin in cerebrospinal fluid: a leptomeningeal protein
por: Reiber, Hansotto, et al.
Publicado: (2012)

Genotyping of cerebrospinal fluid in lung cancer patients with leptomeningeal metastasis
por: Nie, Naifu, et al.
Publicado: (2022)

Experimental Assessment of Leptomeningeal Metastasis Diagnosis in Medulloblastoma Using Cerebrospinal Fluid Metabolomic Profiles
por: Im, Ji Hye, et al.
Publicado: (2021)

Genomic alterations of cerebrospinal fluid cell-free DNA in leptomeningeal metastases of gastric cancer
por: Chen, Xin, et al.
Publicado: (2023)

Epigenetic priming improves salvage chemotherapy in diffuse large B-cell lymphoma via endogenous retrovirus-induced cGAS-STING activation
por: Liu, Jun, et al.
Publicado: (2023)

11. ASSOCIATION OF TUMOR EXPOSURE TO CEREBROSPINAL FLUID SPACES TO LEPTOMENINGEAL DISEASE IN PATIENTS WITH BRAIN METASTASES
por: Patel, Kunal, et al.
Publicado: (2020)

Different Metabolomic and Proteomic Profiles of Cerebrospinal Fluid in Ventricular and Lumbar Compartments in Relation to Leptomeningeal Metastases
por: Kwon, Ji-Woong, et al.
Publicado: (2022)

Diagnostic Value of CYFRA 21-1 in the Cerebrospinal Fluid for Leptomeningeal Metastasis
por: Zhang, Zhen, et al.
Publicado: (2017)

Similar transplant outcomes between haploidentical and unrelated donors after reduced-intensity conditioning with busulfan, fludarabine, and anti-thymocyte globulin in patients with acute leukemia or myelodysplastic syndrome
por: Choi, Mihong, et al.
Publicado: (2020)

Distinctive patterns of peripheral neuropathy across the spectrum of plasma cell disorders
por: Byun, Ja Min, et al.
Publicado: (2019)

Association of HSV-1 and Reduced Oral Bacteriota Diversity with Chemotherapy-Induced Oral Mucositis in Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation
por: Lee, Ahreum, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oogia1eapukoqrc36p7qj5jbue