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Regulation of SETD2 stability is important for the fidelity of H3K36me3 deposition
BACKGROUND: The histone H3K36me3 mark regulates transcription elongation, pre-mRNA splicing, DNA methylation, and DNA damage repair. However, knowledge of the regulation of the enzyme SETD2, which deposits this functionally important mark, is very limited. RESULTS: Here, we show that the poorly char...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542105/ https://www.ncbi.nlm.nih.gov/pubmed/33023640 http://dx.doi.org/10.1186/s13072-020-00362-8 |