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Hindlimb unloading causes regional loading-dependent changes in osteocyte inflammatory cytokines that are modulated by exogenous irisin treatment

Disuse-induced bone loss is characterized by alterations in bone turnover. Accruing evidence suggests that osteocytes respond to inflammation and express and/or release pro-inflammatory cytokines; however, it remains largely unknown whether osteocyte inflammatory proteins are influenced by disuse. T...

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Detalles Bibliográficos
Autores principales: Metzger, Corinne E., Anand Narayanan, S., Phan, Peter H., Bloomfield, Susan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542171/
https://www.ncbi.nlm.nih.gov/pubmed/33083525
http://dx.doi.org/10.1038/s41526-020-00118-4