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Membrane stiffness and myelin basic protein binding strength as molecular origin of multiple sclerosis

Myelin basic protein (MBP) and its interaction with lipids of the myelin sheath plays an important part in the pathology of multiple sclerosis (MS). Previous studies observed that changes in the myelin lipid composition lead to instabilities and enhanced local curvature of MBP-lipid multilayer struc...

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Detalles Bibliográficos
Autores principales:	Krugmann, Benjamin, Radulescu, Aurel, Appavou, Marie-Sousai, Koutsioubas, Alexandros, Stingaciu, Laura R., Dulle, Martin, Förster, Stephan, Stadler, Andreas M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542173/ https://www.ncbi.nlm.nih.gov/pubmed/33028889 http://dx.doi.org/10.1038/s41598-020-73671-3

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