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Copy Number of an Integron-Encoded Antibiotic Resistance Locus Regulates a Virulence and Opacity Switch in Acinetobacter baumannii AB5075

We describe a novel genetic mechanism in which tandem amplification of a plasmid-borne integron regulates virulence, opacity variation, and global gene expression by altering levels of a putative small RNA (sRNA) in Acinetobacter baumannii AB5075. Copy number of this amplified locus correlated with...

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Detalles Bibliográficos
Autores principales:	Anderson, Sarah E., Chin, Chui Yoke, Weiss, David S., Rather, Philip N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542366/ https://www.ncbi.nlm.nih.gov/pubmed/33024041 http://dx.doi.org/10.1128/mBio.02338-20

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