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Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is the leading cause of primary liver cancers. Surveillance of individuals at specific risk of developing HCC, early diagnostic markers, and new therapeutic approaches are essential to obtain a reduction in disease-related mortality. Apurinic/apyrimidinic e...

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Detalles Bibliográficos
Autores principales:	Bazzani, Veronica, Barchiesi, Arianna, Radecka, Dorota, Pravisani, Riccardo, Guadagno, Antonio, Di Loreto, Carla, Baccarani, Umberto, Vascotto, Carlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542375/ https://www.ncbi.nlm.nih.gov/pubmed/33028238 http://dx.doi.org/10.1186/s12885-020-07258-6

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