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Efficient and accurate determination of genome-wide DNA methylation patterns in Arabidopsis thaliana with enzymatic methyl sequencing

BACKGROUND: 5′ methylation of cytosines in DNA molecules is an important epigenetic mark in eukaryotes. Bisulfite sequencing is the gold standard of DNA methylation detection, and whole-genome bisulfite sequencing (WGBS) has been widely used to detect methylation at single-nucleotide resolution on a...

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Detalles Bibliográficos
Autores principales: Feng, Suhua, Zhong, Zhenhui, Wang, Ming, Jacobsen, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542392/
https://www.ncbi.nlm.nih.gov/pubmed/33028374
http://dx.doi.org/10.1186/s13072-020-00361-9

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