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Paclitaxel exposure downregulates miR-522 expression and its downregulation induces paclitaxel resistance in ovarian cancer cells
Paclitaxel resistance is a critical challenge in ovarian cancer treatment. This study aimed to identify microRNAs (miRNAs) that modulate paclitaxel resistance for use as potential therapeutic targets in such settings. Paclitaxel-resistant cell lines were established using two ovarian cancer cell lin...
Autores principales: | Miyamoto, Mayuko, Sawada, Kenjiro, Nakamura, Koji, Yoshimura, Akihiko, Ishida, Kyoso, Kobayashi, Masaki, Shimizu, Aasa, Yamamoto, Misa, Kodama, Michiko, Hashimoto, Kae, Kimura, Tadashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542453/ https://www.ncbi.nlm.nih.gov/pubmed/33028939 http://dx.doi.org/10.1038/s41598-020-73785-8 |
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