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An innovative approach for determining the customized refractive index of ectatic corneas in cataractous patients

The aim of this study is to determine the customized refractive index of ectatic corneas and also propose a method for determining the corneal and IOL power in these eyes. Seven eyes with moderate and severe corneal ectatic disorders, which had been under cataract surgery, were included. At least th...

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Autores principales: Pirhadi, Shiva, Maghooli, Keivan, Jadidi, Khosrow
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542460/
https://www.ncbi.nlm.nih.gov/pubmed/33028843
http://dx.doi.org/10.1038/s41598-020-73492-4
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author Pirhadi, Shiva
Maghooli, Keivan
Jadidi, Khosrow
author_facet Pirhadi, Shiva
Maghooli, Keivan
Jadidi, Khosrow
author_sort Pirhadi, Shiva
collection PubMed
description The aim of this study is to determine the customized refractive index of ectatic corneas and also propose a method for determining the corneal and IOL power in these eyes. Seven eyes with moderate and severe corneal ectatic disorders, which had been under cataract surgery, were included. At least three months after cataract surgery, axial length, cornea, IOL thickness and the distance between IOL from cornea, and aberrometry were measured. All the measured points of the posterior and anterior parts of the cornea converted to points cloud and surface by using the MATLAB and Solidworks software. The implanted IOLs were designed by Zemax software. The ray tracing analysis was performed on the customized eye models, and the corneal refractive index was determined by minimizing the difference between the measured aberrations from the device and resulted aberrations from the simulation. Then, by the use of preoperative corneal images, corneal power was calculated by considering the anterior and posterior parts of the cornea and refractive index of 1.376 and the customized corneal refractive index in different regions and finally it was entered into the IOL power calculation formulas. The corneal power in the 4 mm region and the Barrett formula resulted the prediction error of six eyes within ± 1 diopter. It seems that using the total corneal power along with the Barrett formula can prevent postoperative hyperopic shift, especially in eyes with advanced ectatic disorders.
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spelling pubmed-75424602020-10-14 An innovative approach for determining the customized refractive index of ectatic corneas in cataractous patients Pirhadi, Shiva Maghooli, Keivan Jadidi, Khosrow Sci Rep Article The aim of this study is to determine the customized refractive index of ectatic corneas and also propose a method for determining the corneal and IOL power in these eyes. Seven eyes with moderate and severe corneal ectatic disorders, which had been under cataract surgery, were included. At least three months after cataract surgery, axial length, cornea, IOL thickness and the distance between IOL from cornea, and aberrometry were measured. All the measured points of the posterior and anterior parts of the cornea converted to points cloud and surface by using the MATLAB and Solidworks software. The implanted IOLs were designed by Zemax software. The ray tracing analysis was performed on the customized eye models, and the corneal refractive index was determined by minimizing the difference between the measured aberrations from the device and resulted aberrations from the simulation. Then, by the use of preoperative corneal images, corneal power was calculated by considering the anterior and posterior parts of the cornea and refractive index of 1.376 and the customized corneal refractive index in different regions and finally it was entered into the IOL power calculation formulas. The corneal power in the 4 mm region and the Barrett formula resulted the prediction error of six eyes within ± 1 diopter. It seems that using the total corneal power along with the Barrett formula can prevent postoperative hyperopic shift, especially in eyes with advanced ectatic disorders. Nature Publishing Group UK 2020-10-07 /pmc/articles/PMC7542460/ /pubmed/33028843 http://dx.doi.org/10.1038/s41598-020-73492-4 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Pirhadi, Shiva
Maghooli, Keivan
Jadidi, Khosrow
An innovative approach for determining the customized refractive index of ectatic corneas in cataractous patients
title An innovative approach for determining the customized refractive index of ectatic corneas in cataractous patients
title_full An innovative approach for determining the customized refractive index of ectatic corneas in cataractous patients
title_fullStr An innovative approach for determining the customized refractive index of ectatic corneas in cataractous patients
title_full_unstemmed An innovative approach for determining the customized refractive index of ectatic corneas in cataractous patients
title_short An innovative approach for determining the customized refractive index of ectatic corneas in cataractous patients
title_sort innovative approach for determining the customized refractive index of ectatic corneas in cataractous patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542460/
https://www.ncbi.nlm.nih.gov/pubmed/33028843
http://dx.doi.org/10.1038/s41598-020-73492-4
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