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Oleanolic Acid Decreases IL-1β-Induced Activation of Fibroblast-Like Synoviocytes via the SIRT3-NF-κB Axis in Osteoarthritis

Synovial inflammation is a major pathological feature of osteoarthritis (OA), which is a chronic degenerative joint disease. Fibroblast-like synoviocytes (FLS), localized in the synovial membrane, are specialized secretory cells. During OA synovitis, FLS produce chemokines and cytokines that stimula...

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Detalles Bibliográficos
Autores principales:	Bao, Jiapeng, Yan, Weifeng, Xu, Kai, Chen, Mengyao, Chen, Zhonggai, Ran, Jisheng, Xiong, Yan, Wu, Lidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542488/ https://www.ncbi.nlm.nih.gov/pubmed/33062145 http://dx.doi.org/10.1155/2020/7517219

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