Novel Small-Molecule Inhibitor for the Oncogenic Tyrosine Phosphatase SHP2 with Anti-Breast Cancer Cell Effects

[Image: see text] The oncogenic property of the Src homology phosphotyrosine phosphatase 2 (SHP2) is well-known, but developing specific inhibitors has been very difficult. Based on our previous reports that showed the importance of acidic residues surrounding SHP2 substrate phosphotyrosines for spe...

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Detalles Bibliográficos
Autores principales: Hartman, Zachary, Geldenhuys, Werner J., Agazie, Yehenew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542598/
https://www.ncbi.nlm.nih.gov/pubmed/33043190
http://dx.doi.org/10.1021/acsomega.0c02746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542598/
https://www.ncbi.nlm.nih.gov/pubmed/33043190
http://dx.doi.org/10.1021/acsomega.0c02746

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