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The rise in the number of long-term survivors from different diseases can slow the increase in life expectancy of the total population

BACKGROUND: Recent improvements in life expectancy in many countries stem from reduced mortality from cardiovascular disease and cancer above the age of 60. This is the combined result of decreased incidence and improved survival among those with disease. The latter has led to a higher proportion in...

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Autores principales: Ebeling, Marcus, Meyer, Anna C., Modig, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542716/
https://www.ncbi.nlm.nih.gov/pubmed/33028250
http://dx.doi.org/10.1186/s12889-020-09631-3
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author Ebeling, Marcus
Meyer, Anna C.
Modig, Karin
author_facet Ebeling, Marcus
Meyer, Anna C.
Modig, Karin
author_sort Ebeling, Marcus
collection PubMed
description BACKGROUND: Recent improvements in life expectancy in many countries stem from reduced mortality from cardiovascular disease and cancer above the age of 60. This is the combined result of decreased incidence and improved survival among those with disease. The latter has led to a higher proportion in the population of people with a past history of disease. This is a group with higher mortality than the general population. How growing shares of persons with past history of disease and improved survival with disease have affected changes in life expectancy of the total population is the objective of this paper. METHODS: Using register data for the total Swedish population, we stratified the population based on whether individuals have been diagnosed with myocardial infarction, stroke, hip fracture, colon cancer, or breast cancer. Using a novel decomposition approach, we decomposed the changes in life expectancy at age 60 between 1994 and 2016 into contributions from improved survival with disease and from changes in proportion of people with past history of disease. RESULTS: Improvements in survival from disease resulted in gains of life expectancy for the total population. However, while the contributions to life expectancy improvements from myocardial infarction, stroke and breast cancer were substantial, the contributions from the other diseases were minor. These gains were counteracted, to various degrees, by the increasing proportion of people with raised mortality due to a past history of disease. For instance, the impact on life expectancy by improved survival from breast cancer was almost halved by the increasing share of females with a past history of breast cancer. CONCLUSION: Rising numbers of survivors of different diseases can slow the increase in life expectancy. This dynamic may represent the costs associated with successful treatment of diseases, and thus, a potential “failure of success.” This dynamic should be considered when assessing mortality and life expectancy trends. As populations are aging and disease survival continues to improve, this issue is likely to become even more important in the future.
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spelling pubmed-75427162020-10-08 The rise in the number of long-term survivors from different diseases can slow the increase in life expectancy of the total population Ebeling, Marcus Meyer, Anna C. Modig, Karin BMC Public Health Research Article BACKGROUND: Recent improvements in life expectancy in many countries stem from reduced mortality from cardiovascular disease and cancer above the age of 60. This is the combined result of decreased incidence and improved survival among those with disease. The latter has led to a higher proportion in the population of people with a past history of disease. This is a group with higher mortality than the general population. How growing shares of persons with past history of disease and improved survival with disease have affected changes in life expectancy of the total population is the objective of this paper. METHODS: Using register data for the total Swedish population, we stratified the population based on whether individuals have been diagnosed with myocardial infarction, stroke, hip fracture, colon cancer, or breast cancer. Using a novel decomposition approach, we decomposed the changes in life expectancy at age 60 between 1994 and 2016 into contributions from improved survival with disease and from changes in proportion of people with past history of disease. RESULTS: Improvements in survival from disease resulted in gains of life expectancy for the total population. However, while the contributions to life expectancy improvements from myocardial infarction, stroke and breast cancer were substantial, the contributions from the other diseases were minor. These gains were counteracted, to various degrees, by the increasing proportion of people with raised mortality due to a past history of disease. For instance, the impact on life expectancy by improved survival from breast cancer was almost halved by the increasing share of females with a past history of breast cancer. CONCLUSION: Rising numbers of survivors of different diseases can slow the increase in life expectancy. This dynamic may represent the costs associated with successful treatment of diseases, and thus, a potential “failure of success.” This dynamic should be considered when assessing mortality and life expectancy trends. As populations are aging and disease survival continues to improve, this issue is likely to become even more important in the future. BioMed Central 2020-10-07 /pmc/articles/PMC7542716/ /pubmed/33028250 http://dx.doi.org/10.1186/s12889-020-09631-3 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Ebeling, Marcus
Meyer, Anna C.
Modig, Karin
The rise in the number of long-term survivors from different diseases can slow the increase in life expectancy of the total population
title The rise in the number of long-term survivors from different diseases can slow the increase in life expectancy of the total population
title_full The rise in the number of long-term survivors from different diseases can slow the increase in life expectancy of the total population
title_fullStr The rise in the number of long-term survivors from different diseases can slow the increase in life expectancy of the total population
title_full_unstemmed The rise in the number of long-term survivors from different diseases can slow the increase in life expectancy of the total population
title_short The rise in the number of long-term survivors from different diseases can slow the increase in life expectancy of the total population
title_sort rise in the number of long-term survivors from different diseases can slow the increase in life expectancy of the total population
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542716/
https://www.ncbi.nlm.nih.gov/pubmed/33028250
http://dx.doi.org/10.1186/s12889-020-09631-3
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