Mammalian Expression and In Situ Biotinylation of Extracellular Protein Targets for Directed Evolution

[Image: see text] Directed evolution is a powerful tool for the selection of functional ligands from molecular libraries. Extracellular domains (ECDs) of cell surface receptors are common selection targets for therapeutic and imaging agent development. Unfortunately, these proteins are often post-tr...

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Detalles Bibliográficos
Autores principales: Grindel, Brian J., Engel, Brian J., Hall, Carolyn G., Kelderhouse, Lindsay E., Lucci, Anthony, Zacharias, Niki M., Takahashi, Terry T., Millward, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542843/
https://www.ncbi.nlm.nih.gov/pubmed/33043224
http://dx.doi.org/10.1021/acsomega.0c03990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542843/
https://www.ncbi.nlm.nih.gov/pubmed/33043224
http://dx.doi.org/10.1021/acsomega.0c03990

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