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Mammalian Expression and In Situ Biotinylation of Extracellular Protein Targets for Directed Evolution
[Image: see text] Directed evolution is a powerful tool for the selection of functional ligands from molecular libraries. Extracellular domains (ECDs) of cell surface receptors are common selection targets for therapeutic and imaging agent development. Unfortunately, these proteins are often post-tr...
Autores principales: | Grindel, Brian J., Engel, Brian J., Hall, Carolyn G., Kelderhouse, Lindsay E., Lucci, Anthony, Zacharias, Niki M., Takahashi, Terry T., Millward, Steven W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542843/ https://www.ncbi.nlm.nih.gov/pubmed/33043224 http://dx.doi.org/10.1021/acsomega.0c03990 |
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