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Oxidative Rearrangement of Stilbenes to 2,2-Diaryl-2-hydroxyacetaldehydes
[Image: see text] A one-pot oxone-mediated/iodine-catalyzed oxidative rearrangement of stilbenes leading to 2,2-diaryl-2-hydroxyacetaldehydes is described. Control experiments revealed that a 2,2-diarylacetaldehyde was initially formed that undergoes subsequent α-hydroxylation. The resulting α-hydro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542859/ https://www.ncbi.nlm.nih.gov/pubmed/33043198 http://dx.doi.org/10.1021/acsomega.0c03328 |
| Sumario: | [Image: see text] A one-pot oxone-mediated/iodine-catalyzed oxidative rearrangement of stilbenes leading to 2,2-diaryl-2-hydroxyacetaldehydes is described. Control experiments revealed that a 2,2-diarylacetaldehyde was initially formed that undergoes subsequent α-hydroxylation. The resulting α-hydroxyaldehydes have been subjected to a one-pot Still–Gennari olefination followed by cyclization, leading to 5,5-diaryl-γ-butenolides. |
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