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Correntropy induced loss based sparse robust graph regularized extreme learning machine for cancer classification

BACKGROUND: As a machine learning method with high performance and excellent generalization ability, extreme learning machine (ELM) is gaining popularity in various studies. Various ELM-based methods for different fields have been proposed. However, the robustness to noise and outliers is always the...

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Autores principales: Ren, Liang-Rui, Gao, Ying-Lian, Liu, Jin-Xing, Shang, Junliang, Zheng, Chun-Hou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542897/
https://www.ncbi.nlm.nih.gov/pubmed/33028187
http://dx.doi.org/10.1186/s12859-020-03790-1
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author Ren, Liang-Rui
Gao, Ying-Lian
Liu, Jin-Xing
Shang, Junliang
Zheng, Chun-Hou
author_facet Ren, Liang-Rui
Gao, Ying-Lian
Liu, Jin-Xing
Shang, Junliang
Zheng, Chun-Hou
author_sort Ren, Liang-Rui
collection PubMed
description BACKGROUND: As a machine learning method with high performance and excellent generalization ability, extreme learning machine (ELM) is gaining popularity in various studies. Various ELM-based methods for different fields have been proposed. However, the robustness to noise and outliers is always the main problem affecting the performance of ELM. RESULTS: In this paper, an integrated method named correntropy induced loss based sparse robust graph regularized extreme learning machine (CSRGELM) is proposed. The introduction of correntropy induced loss improves the robustness of ELM and weakens the negative effects of noise and outliers. By using the L(2,1)-norm to constrain the output weight matrix, we tend to obtain a sparse output weight matrix to construct a simpler single hidden layer feedforward neural network model. By introducing the graph regularization to preserve the local structural information of the data, the classification performance of the new method is further improved. Besides, we design an iterative optimization method based on the idea of half quadratic optimization to solve the non-convex problem of CSRGELM. CONCLUSIONS: The classification results on the benchmark dataset show that CSRGELM can obtain better classification results compared with other methods. More importantly, we also apply the new method to the classification problems of cancer samples and get a good classification effect.
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spelling pubmed-75428972020-10-13 Correntropy induced loss based sparse robust graph regularized extreme learning machine for cancer classification Ren, Liang-Rui Gao, Ying-Lian Liu, Jin-Xing Shang, Junliang Zheng, Chun-Hou BMC Bioinformatics Methodology Article BACKGROUND: As a machine learning method with high performance and excellent generalization ability, extreme learning machine (ELM) is gaining popularity in various studies. Various ELM-based methods for different fields have been proposed. However, the robustness to noise and outliers is always the main problem affecting the performance of ELM. RESULTS: In this paper, an integrated method named correntropy induced loss based sparse robust graph regularized extreme learning machine (CSRGELM) is proposed. The introduction of correntropy induced loss improves the robustness of ELM and weakens the negative effects of noise and outliers. By using the L(2,1)-norm to constrain the output weight matrix, we tend to obtain a sparse output weight matrix to construct a simpler single hidden layer feedforward neural network model. By introducing the graph regularization to preserve the local structural information of the data, the classification performance of the new method is further improved. Besides, we design an iterative optimization method based on the idea of half quadratic optimization to solve the non-convex problem of CSRGELM. CONCLUSIONS: The classification results on the benchmark dataset show that CSRGELM can obtain better classification results compared with other methods. More importantly, we also apply the new method to the classification problems of cancer samples and get a good classification effect. BioMed Central 2020-10-07 /pmc/articles/PMC7542897/ /pubmed/33028187 http://dx.doi.org/10.1186/s12859-020-03790-1 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Methodology Article
Ren, Liang-Rui
Gao, Ying-Lian
Liu, Jin-Xing
Shang, Junliang
Zheng, Chun-Hou
Correntropy induced loss based sparse robust graph regularized extreme learning machine for cancer classification
title Correntropy induced loss based sparse robust graph regularized extreme learning machine for cancer classification
title_full Correntropy induced loss based sparse robust graph regularized extreme learning machine for cancer classification
title_fullStr Correntropy induced loss based sparse robust graph regularized extreme learning machine for cancer classification
title_full_unstemmed Correntropy induced loss based sparse robust graph regularized extreme learning machine for cancer classification
title_short Correntropy induced loss based sparse robust graph regularized extreme learning machine for cancer classification
title_sort correntropy induced loss based sparse robust graph regularized extreme learning machine for cancer classification
topic Methodology Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542897/
https://www.ncbi.nlm.nih.gov/pubmed/33028187
http://dx.doi.org/10.1186/s12859-020-03790-1
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