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The Human-Specific STING Agonist G10 Activates Type I Interferon and the NLRP3 Inflammasome in Porcine Cells

Pigs have anatomical and physiological characteristics comparable to those in humans and, therefore, are a favorable model for immune function research. Interferons (IFNs) and inflammasomes have essential roles in the innate immune system. Here, we report that G10, a human-specific agonist of stimul...

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Detalles Bibliográficos
Autores principales:	Ming, Sheng-Li, Zeng, Lei, Guo, Yu-Kun, Zhang, Shuang, Li, Guo-Li, Ma, Ying-Xian, Zhai, Yun-Yun, Chang, Wen-Ru, Yang, Le, Wang, Jiang, Yang, Guo-Yu, Chu, Bei-Bei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543045/ https://www.ncbi.nlm.nih.gov/pubmed/33072119 http://dx.doi.org/10.3389/fimmu.2020.575818

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